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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

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A | Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。秋日的建昌县药王庙镇西山，尽管榛子已经采摘完毕，但仍呈现一派忙碌景象，有的在侍弄苗木，有的在厂房里挑选、翻炒榛子。看着热火朝天的场面，59岁的周广兴信心十足，决定扩大种植规模，创出品牌，让榛子树真正成为共同致富的“摇钱树”。 8年前，通过实地考察，周广兴发现西山景色优美，灌木丛生，地理位置优越，非常适合榛子树生长。“我了解榛子树的生长习性，如果把山开垦出来，利用自己的经验、技术，不仅能让荒山变成绿洲，而且还能造福于民。” 拿定主意，周广兴就到外地进一步学习、请教，并从省农科院引进新品种榛子苗。“这种苗木适合在山上生长，果实口感好、个头儿大，营养丰富，价格公道。” 经过合理有效操作，周广兴将西山承包了下来。他与员工辛苦付出，天旱了打井，涝了泄洪；树叶蔫了找病根儿，间距近了重栽……在大家共同努力下，1000余亩、10万棵榛子树郁郁葱葱。每年的8月份，榛子树的果实逐步成熟。至9月份，果实全部下树。之后，员工开始挑选榛子，型号差不多的收集在一起，以便区分精品、普通等品质。这些活计，目前已经干得差不多了，到11月中旬将全部完工。 “今年收成不错，能产近7万斤榛子，产值能达到100余万元。”周广兴说，“充分利用山上的地块，明年再栽种近万棵榛子树。” 几年来，凭借良好的信誉及科学管理，这里的榛子闯出了名堂，本地及外地的消费者或前来购买，或网上订购，至11月底，基本售空。同时，由周广兴牵头任支部书记，成立兴发种植养殖合作社党支部。到了年底，合作社将部分收益给一些村民分红，极大地提高了村民生产积极性。 “党群致富有新意，生产经营有创意。